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Supply Physcion

Posted at: Offers to Sell and Export | Posted on: Mon 13 Aug, 2007 3:50 am |
Products Photos CatalogPhyscion Photos Catalog


CAS #: 521-61-9

Molecular formula: C16H12O5

Molucular weight: 284.26

Formulation: White


Purity: 99%

1,8-Dihydroxyanthraquinones, present in laxatives, fungi imperfecti, Chinese herbs and possibly vegetables, are in debate as human carcinogens. We screened a variety of vegetables (cabbage lettuce, beans, peas), some herbs and herbal-flavoured liquors for their content of the 'free' anthraquinones emodin, chrysophanol and physcion. For qualitative and quantitative analysis, reversed-phase HPLC (RP-LC), gas chromatography-mass spectrometry (GC-MS) and RP-LC-MS were used. The vegetables showed a large batch-to-batch variability, from 0.04 to 3.6, 5.9 and 36 mg total anthraquinone per kg fresh weight in peas, cabbage lettuce, and beans, respectively. Physcion predominated in all vegetables. In the herbs grape vine leaves, couch grass root and plantain herb, anthraquinones were above the limit of detection. Contents ranged below 1 mg/kg (dry weight). All three anthraquinones were also found in seven of 11 herbal-flavoured liquors, in a range of 0.05 mg/kg to 7.6 mg/kg. The genotoxicity of the analysed anthraquinones was investigated in the comet assay, the micronucleus test and the mutation assay in mouse lymphoma L5178Y tk+/- cells. Emodin was genotoxic, whereas chrysophanol and physcion showed no effects. Complete vegetable extract on its own did not show any effect in the micronucleus test. A lettuce extract completely abolished the induction of micronuclei by the genotoxic anthraquinone danthron. Taking into consideration the measured concentrations of anthraquinones, estimated daily intakes, the genotoxic potency, as well as protective effects of the food matrix, the analysed constituents do not represent a high priority genotoxic risk in a balanced human diet

Company Contact:

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Contact Name: Ye Lixia
Company Name: Shaanxi Sciphar Biotechnology Co., Ltd.
Email: Email
Tel: +86-29-88353228 , +86-29-88389752 , +86-29-88353265
Fax: +86-29-88389961
Street Address: No.11 Tangxing Road, Hi-
Tech Development Zone, Xian city, Shaanxi
Province, China Postcode: 710075
Website: http://www.sciphar.com
Member name: wwwscipharcom
Country: China-CN China
Member Since: 13 August 2007
Total Leads: 58 wwwscipharcom Import Export Business Leads
Business focus: Natural Herb Extract, Ingredients, Intermediates, Chemical, Pharmaceutical
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  • Physcion Cas 521-61-9 Physcion Cas 521-61-9 - By chengdumaochen - On Sun 28 Jun, 2009 1:35 pm: physcion cas 521-61-9 cas 521-61-9 einecs 208-315-7 molecular formula c16h12o5 molecular weight 284 27 murity amp gt 98% high purity monomer....oit

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