|
|
|
|
|
|
| |
Supply Topotecan Hcl
Posted at: TradersCity --> Offers to Sell and Export
Posted on: Mon 13 Aug, 2007 4:09 am
Topotecan HCl
CAS: 119413-54-6
Molecular formula: C23H23N3O5. HCl
Molecular weight: 457.91
Purity: 98 percent By HPLC
Topotecan, a semi-synthetic derivative of camptothecin (a plant alkaloid obtained from the Camptotheca acuminata tree), is an anti-tumor drug with topoisomerase I-inhibitory activity similar to irinotecan. Topotecan interferes with the growth of cancer cells, which are eventually destroyed. Since the growth of normal cells may also be affected by the medicine, other effects may also occur. Unlike irinotecan, topotecan is found predominantly in the inactive carboxylate form at neutral pH and it is not a prodrug.
Topotecan has the same mechanism of action as irinotecan. Topoisomerase I relieves torsional strain in DNA by inducing reversible single strand breaks. Topotecan binds to the topoisomerase I-DNA complex and prevents religation of these single strand breaks. The cytotoxicity of topotecan is thought to be due to double strand DNA damage produced during DNA synthesis when replication enzymes interact with the ternary complex formed by topotecan, topoisomerase I and DNA. Mammalian cells cannot efficiently repair these double strand breaks.
_________________
Contact Name: Ye Lixia
Company Name: Shaanxi Sciphar Biotechnology Co., Ltd.
Address: No.11 Tangxing Road, Hi-Tech Development Zone, Xian city, Shaanxi Province, China
Postcode: 710075
Tel: +86-29-88353228, +86-29-88389752, +86-29-88353265
Fax: +86-29-88389961
E-mail: sales03@sciphar.com
Web Site: http://www.sciphar.com
|
Get your Free TradersCity Browser ToolSearch, Visit, and Post to TradersCity Quickly and Easily From Your Computer at any Time 
Download it here
|
Posted By wwwscipharcom
Country:  China
Member Since: 13 August 2007
Total Leads: 58
Business focus: natural herb extract, ingredients, intermediates, chemical, pharmaceutical
  
|
|
|
|
|
|
|
|
|
Similar Leads ( topotecan hcl )
| Import Export Lead |
Posted By |
Posted |
Preview |
|
ShandongBoyuanChemical |
Sat 24 Nov, 2007 4:19 pm |
topotecan hydrochloride
cas 119413-54-6
standard enterprise standard
purpose anticancer drugs |
|
igulff |
Sat 27 Jan, 2007 10:53 am |
quinine hcl quinine sulphate quinine anhydrous quinine bisulphate quinine hydrochloride quinine we take this opportunity to introduce ourselves as processors amp amp exporters of api s we offer the below products
quinine anhydrous
quinine ....oit |
|
ls002huiying |
Wed 11 Apr, 2007 12:59 am |
pioglitazone hcl pharmaceuticals cas no 112529-15-4
thanks a lot for your kind attention if you are interested in our products please don t hesitate to contact us for further informa....oit |
|
huangxiaoji |
Tue 29 May, 2007 1:17 am |
racepinephrine hcl
cas 329-63-5
it can comply with usp
we are the largest manufacturer in china
we have dmf ....oit |
|
huangxiaoji |
Tue 29 May, 2007 1:24 am |
xylometazoline hcl
cas 1218-35-5
it comply with usp ep
we are the largest manufacturer in china having gmp certification
we have dmf ....oit |
|
duanlongke |
Sat 04 Aug, 2007 5:44 am |
sell nitromethane hydroxylamine hcl dimethyl sulfate methyl p tolyl sulfone
we shandong xinghui chemical co ltd is a manufacturer of the following product
1 nitromethane 99% 99 5% 99 9%
2 hydroxylamine hydrochl....oit |
|
duanlongke |
Sat 04 Aug, 2007 5:46 am |
sell hydroxylamine hcl
hydroxylamine hydrochloride
molecular formate nh2oh hcl
molal weight 69 5
physicochemical property white crystal easy deliquescence dissolve i....oit |
|
wwwscipharcom |
Mon 13 Aug, 2007 3:58 am |
hcl
cas # 115-53-7
molecular formula g19h23no4
molecular weight 329 38
appearance white powder
purity 98% by hplc
sinamenine hcl.... |
|
wwwscipharcom |
Mon 13 Aug, 2007 4:03 am |
supply yohimbe hcl
yohimbe hcl
cas # 146-48-5
molecular formula c21h26o3
molecular weight 354 45
purity yohimbine 1%--98% test by hplc
yohimbe is an....oit |
|
wwwscipharcom |
Mon 13 Aug, 2007 4:08 am |
hcl trihydrate
cas # 136572-09-3
molecular formula c33h38n4o6-hcl-3h2o
molucular weight 677
synonyms cpt-11 camptosar
formulation .... |
|
|
|
|
Free Magazine Subscription
|
|
|
|
|
|
Testimonials
20 visitors now from: 
10 USA | 
1 Switzerland | 
1 Indonesia | 
1 Iran | 
1 Korea | 
1 Kuwait | 
1 Malaysia | 
1 Philippines | 
1 Poland | 
1 UK | 
1 Yemen |
