Product No.: OHI-000102 CAS No.： Active Ingredient: Oxymatrine Matrine Specification:
90% Test Method： HPLC Related Document Request a Quote Free Samples Tell friends Print This Page! Kuhseng Extract Sophora flavescens Oxymatrine Matrine
Ku Shen is a Chinese herb with a lot of promise. Although it has been used by traditional practitioners for thousands of years, it is now the subject of some very exciting clinical and pharmacological research, revealing its powerful therapeutic value for a surprisingly wide range of conditions - from dysentery and asthma to cancer and hepatitis.
Ku Shen is the Chinese term for the root of Sophora flavescens, a member of the Bean and Pea family, Leguminosae. Found growing wild throughout China in sunny meadows and roadsides, it is also cultivated, mostly in the Shanxi and Hubei provinces. While the plant contains a rich cornucopia of useful chemical constituents, as most herbs do, current research is focused primarily on 2 of its quinolizodine alkaloid constituents, matrine and oxymatrine. S. flavescens naturally contains about 2% of these compounds in its root stock.
Other species of Sophora also contain these valuable constituents. S. japonica and S. angustifolia are also called Ku Shen in the Chinese Pharmacopeia, because in Traditional Chinese Medicine, they were found to have properties and applications nearly equivalent to those of S. flavescens. S. subprostrata is also quite similar but is distinguished as Shan Dou Gen. Both types of TCM herb are bitter, cold "heat clearing" herbs, but Ku Shen is thought to "dry dampness" whereas Shan Dou Gen is thought to "clean toxins." S. alopecuroides is also used in traditional medicine. Of all the alkaloid rich Sophoras, though, S. flavescens is most common and most commonly used. It is much like the usage prevalence of Echinacea purpurea over its cousins in the United States.
Ku Shen is remarkable in the diversity of conditions for which it has shown positive benefit. It has been used safely with significant results to treat asthma, bronchitis, cardiac arrhythmia, ulcer, bacterial and candida infections, eczema, neurodermatitis, psoriasis, vaginitis, hepatitis B and C, dysentery, conjunctivitis, parasites, fever, inflammation, insomnia, and cancer. Wow! With so many positive therapeutic applications, it is no wonder that clinical and pharmacological researchers are excited about investigating this herb and its alkaloids. Following is a very brief description of their findings:
Asthma and Bronchitis
In animal studies, the alkaloid matrine was found to be as effective as methylxanthine bronchodilator aminophylline without its stimulatory side effects. Oxymatrine was also found to inhibit histamine release in mice. Sophocarpine, another alkaloid in Ku Shen, was found be antitussive, inhibiting the urge to cough, while its flavone compounds demonstrated expectorant effects. 517 cases of asthmatic bronchitis were treated with Ku Shen with an 86.5% effectiveness and 38.8% marked effectiveness rate.
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